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In January 2005, Madumekala Udayawanthi was an 11-year-old girl with the height of a 3-year-old (100cm = 39.37 inches) when she was first introduced to us in February 2005 at the Children’s clinic in the Mawella camp in Sri Lanka. At the age of three years, she had been hit by a bus and was in a coma for a long time. Her pituitary gland ended up being severely damaged because of this trauma. At the age of eight years, Madumekala was diagnosed with panhypopituitarism. FYI: The pituitary gland is called the master endocrine gland of the body because it controls function over other endocrine organs. The anterior pituitary produces the hormones thyrotropin (thyroid-stimulating hormone [TSH]), corticotropin (adrenocorticotropin [ACTH]), luteinizing hormone (LH), follicle-stimulating hormone (FSH), growth hormone (GH), and prolactin (PRL). The anterior pituitary is controlled by specific hypothalamic-releasing hormones. The posterior pituitary produces vasopressin (antidiuretic hormone [ADH]) and oxytocin. Panhypopituitarism is a condition of inadequate or absent production of the anterior pituitary hormones. The signs and symptoms are diverse. Manifestations of anterior hypopituitarism include hypoglycemia and poor growth. Making a Huge Difference
Update: January
28, 2007
Update: October 2006
Madumekala Udayawanthi Ubeywarna is now 12 years old and continues to do well under the treatment with Human Growth Hormone, gaining height and weight. Her family, having lost their house and all their possessions in the tsunami of December 2004, just moved out of the refugee camp, where we met her in February 2005 into a newly built village for 100 families, the I.S.P. Tsunami Village Yayawatta, Palapotha, Seenimodara, close to the city of Tangalle, Sri Lanka. Madumekala visits the clinic at Karapitiya Hospital in Galle every two weeks with her mother to be seen by Prof. Sujeewa Amarasena, the Head of the Department of Pediatrics of the University of Ruhuna in Galle, who oversees her treatment. Since the family is very poor and their only income right now is 2,000 Rupees ($20) per month, we are providing the bus fare for the hospital visits as well as the funding for the treatment with HGH. Minerva Fernando, Real Medicine's coordinator in Sri Lanka, also started to supply Madumekala with additional food to support her treatment. The move to the new village makes it more difficult for the children to attend school. They were accustomed to walk to their school, which now is nearly impossible. We are hiring a trishaw for Madumekala and two more children to take them to school and pick them up (400 Rupees = $4/month). Thank you so much to our generous donors, who are making sure that Madumekala's treatment will be taken care of for the next years to come! We will keep you posted on her progress. Update: February 2005 – April 2006 Madumekala was started on hormone replacement therapy (hydrocortisone and thyroxine) at that time, but the parents could not afford the treatment with growth hormone ($450/month). Real Medicine decided to support Madumekala’s treatment so that she would have a chance to reach an adult height and live a normal life. We were able to provide treatment for her starting in March 2005 for the entire upcoming year with the help of Care Sri Lanka (www.caresrilanka.com). Thank you! Prof. Sujeewa Amaresena, the Head of the Department of Pediatrics of the University of Ruhuna in Galle, generously offered to oversee her treatment.
By June 2005, after two months of treatment with growth hormone, Madumekala had already responded very well. She had grown more than an inch and her body and face had
started to change. Her mother is driving with her by bus to Galle (4-hour-drive) once a month to see Dr. Sujeewa Amarasena and to pick up the medication. Right now, she
is treated with growth hormone, thyroxine and hydrocortisone.
We saw Madumekala again in March 2006, by then she had grown a total of 9cm (3.54 inches) under the treatment. And she is becoming more and more of a happy little girl.
To continue the treatment, we need about $480/month for the next 4 to 5 years to make it possible for Madumekala to reach an acceptable height. The goal is to treat
Madumekala with growth hormone until she reaches puberty. |
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